Job Title: Associate Scientist - Gene Therapy
Purpose of Job
The role involves overseeing and guiding downstream processing activities in the Cell and Gene Therapy DSP laboratory. This includes hands-on execution, method development, equipment handling, and mentoring of junior team members. The position plays a key role in optimizing processes and supporting development goals aligned with CGT strategies.
Skill Required
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In-depth knowledge of downstream processing techniques and equipment used in biotherapeutic or gene therapy manufacturing
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Proven expertise in chromatography, TFF, and related purification processes
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Strong documentation and compliance orientation, especially in GLP/GDP environments
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Ability to analyze data, troubleshoot process issues, and lead continuous improvement
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Team leadership experience with effective communication and mentoring skills
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Exposure to Cell and Gene Therapy concepts is a strong advantage
Roles and Responsibilites
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Supervise and guide downstream process development for gene therapy products, including buffer prep, cell lysis, clarification, centrifugation, and chromatography techniques.
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Apply scientific knowledge to develop and optimize DSP processes based on principles and methodologies relevant to CGT.
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Operate and troubleshoot DSP equipment such as preparative chromatography systems, TFF units, pH/conductivity meters, centrifuges, and spectrophotometers.
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Ensure proper data generation, compilation, and review for experiments performed; ensure traceability and integrity in scientific documentation.
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Support technology transfer, scale-up, and process improvement initiatives across CGT projects.
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Provide training and mentorship to junior staff; ensure consistent skill development within the DSP function.
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Contribute to internal knowledge sharing and ensure scientific presentations and reports meet project standards.
Qualification Required
MTECH Biotechnology/Bioprocess Technology, MSc Biotechnology
Competencies
Relevant skills / Industry experience
3-5 years of experience in gene therapy/biologics
Biotech, Ahmedabad, GJ, IN, 382213